Second Harmonic Super-resolution Microscopy for Quantification of mRNA at Single Copy Sensitivity
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چکیده
منابع مشابه
Second Harmonic Super-resolution Microscopy for Quantification of mRNA at Single Copy Sensitivity
Cell-specific information on the quantity and localization of key mRNAs at single copy sensitivity in single cells is critical for evaluating basic cellular process, disease risk, and efficacy of therapy. Quantification of overexpressed mRNAs beyond the diffraction limit is constrained by the optical property of the probes and microscopy techniques. In this report, nanosized barium titanium oxi...
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ژورنال
عنوان ژورنال: ACS Nano
سال: 2014
ISSN: 1936-0851,1936-086X
DOI: 10.1021/nn505096t